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Description

The internalized glucose molecule is initially converted to glucose 6-phosphate (G6P) by hexokinase, and then it produces pyruvate through glycolysis as well as abundant reduced nicotinamide adenine dinucleotide phosphate (NADPH) and ribose 5-phosphate through the PPP [17]

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This process recruits RNA-dependent RNA polymerase 6 to the 3 end of the target, a phenomenon known as transitive silencing [50]

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